Resistance to TB drugs

Primary MDR-TB occurs in patients who have not previously been infected with TB but who become infected with a strain that is resistant to treatment. Acquired MDR-TB occurs in patients during treatment with a drug regimen that is not effective at killing the particular strain of TB with which they have been infected Treatment of MDR-TB requires treatment with second-line drugs, usually four or more anti-TB drugs for a minimum of 6 months, and possibly extending for 18–24 months if rifampin resistance has been identified in the specific strain of TB with which the patient has been infected.In general, second-line drugs are less effective, more toxic and much more expensive than first-line drugs. Under ideal program conditions, MDR-TB cure rates can approach 70%.

  • Intrinsic drug resistance
  • Acquired drug resistance
  • Resistance and biological fitness
  • New drugs and new targets
  • new resistance mechanisms

Related Conference of Resistance to TB drugs

March 17-18, 2025

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6th International Conference on Molecular Microbiology

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13th World Congress and Expo on Applied Microbiology

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